Scientific Studies

Recurrent Uncomplicated Urinary Tract Infections in Women

AUA/CUA/SUFU Guideline (2022) Panel Members Jennifer Anger, MD, MPH; Una Lee, MD; A. Lenore Ackerman, MD, PhD; Roger Chou, MD; Bilal Chughtai, MD; J. Quentin Clemens, MD; Duane Hickling, MD, MSCI; Anil Kapoor, MD; Kimberly S. Kenton, MD, MS; Melissa R. Kaufman, MD, PhD; Mary Ann Rondanina, Yahir A. Santiago-Lastra, MD; Ann Stapleton, MD; Lynn … Continue reading

Cranberries for preventing urinary tract infections

Review published in The Cochrane Library, 2012 PLAIN LANGUAGE SUMMARY Cranberries (usually as cranberry juice) have been used to prevent urinary tract infections (UTIs). Cranberries contain a substance that can prevent bacteria from sticking on the walls of the bladder. This may help prevent bladder and other UTIs. This review identified 24 studies (4473 participants) … Continue reading

Catheter-associated urinary tract infections

Thomas, 2017 Does cranberry have a role in catheter-associated urinary tract infections? Link to view full … Continue reading

Variability of commercial cranberry products for the prevention of uropathogenic bacterial adhesion

Chughtai, 2016 Conclusion excerpt: Despite clinical trials showing the efficacy of cranberry in preventing urinary tract infections, the actual antiadhesion activity and concentration of active proantho- cyanidins in commercially available supplements is highly variable. In this study, several products contained virtually no active cranberry compounds. The clinical significance of this suggests that, although some are … Continue reading


Urell, 2008 Cranberry clinical evidence Link to view full … Continue reading

Cranberry (Vaccinium macrocarpon) and urinary tract infections: study and review of the literature

Lavigne, 2007 Link to view full … Continue reading

Use of cranberry for prophylaxis of uncomplicated recurrent urinary tract infections 

European Association of Urology, 2010 Link to view full PDF: Abstract: Over the last few years, an increase in the use of cranberry (C) has been noted for the following two reasons: i) the high number of UTIs has lead to increased antibiotic use and thus increased antibi- otic resistance; and ii) the main mecha- … Continue reading

In-vitro and in-vivo evidence of dose-dependent decrease of uropathogenic Escherichia coli virulence after consumption of commercial Vaccinium macrocarpon (cranberry) capsules 

Lavigne, 2007 This study evaluated the antibacterial efficacy of the consumption of cranberry capsules vs. placebo in the urine of healthy volunteers. A first double-blind, randomised, crossover trial involved eight volunteers who had followed three regimens, with or without cranberry, with a wash-out period of at least 6 days between each regimen. Twelve hours after … Continue reading

Prophylaxis of rUTIs compared with antibiotic 

Uberos, 2012 Cranberry syrup vs trimethoprim in the prophylaxis of recurrent urinary tract infections among children: a controlled trial Link to view full PDF: … Continue reading

Asymptomatic bacteriuria after cystoplasty 

Botto Effectiveness of a cranberry (Vaccinium macrocarpon) preparation in reducing asymptomatic bacteriuria in patients with an ileal enterocystoplasty  Link to view full … Continue reading

Only soluble PACs from concentrated cranberry juice extract are responsible for Anti Adhesion Activity 

Howell, 2021 Differences in Urinary Bacterial Anti-Adhesion Activity after Intake of Cranberry Dietary Supplements with Soluble versus Insoluble Proanthocyanidins Link to view full … Continue reading

Target dose for UTI prevention  

Howell, 2010 Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. Link to view full … Continue reading

Recurrent Uncomplicated Urinary Tract Infections in Women

AUA/CUA/SUFU Guideline (2022) Panel Members Jennifer Anger, MD, MPH; Una Lee, MD; A. Lenore Ackerman, MD ...